RNAi Experiment: Simmer:C35D10.4:Screen |
Ace View of Simmer:C35D10.4:Screen
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Genes Inhibited |
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Gene Inhibited |
C35D10.4 (coq-8) |
Description of "C35D10.4" |
coq-8 encodes a protein orthologous to COQ8 from S. cerevisiae and homologous to ABC1 from S. cerevisiae and AarF from E. coli; COQ-8 is required for ubiquinone biosynthesis and for normally short lifespan; the biochemical function of COQ-8 is unknown, but it may be a chaperonin; coq-8(RNAi) animals have reduced levels of coenzyme Q8, coenzyme Q9, and superoxide, and have abnormally long lifespans. |
KOG Annotation  |
ABC (ATP binding cassette) 1 protein
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (III:4863494..4864692)
Transcript overlap: 978 nt |
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Sliding Window |
Raw score: 915
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "C35D10.4" Links |
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Simmer:C35D10.4:Screen Phenotypes |
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Larval |
Gro
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Simmer:C35D10.4:Screen Experiment Details |
Ace View |
Laboratory |
NL |
RNAi Reagent & Type |
sjj_C35D10.4 (PCR_reagent) |
Strain |
NL4256 rrf-3(pk1426) |
Reference |
Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." |
Date |
2003-10-01 |
Gene Plot of C35D10.4 |
Browse using GBrowse
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