| RNAi Experiment: Simmer:F01G12.5a:Repeat_a |
Ace View of Simmer:F01G12.5a:Repeat_a
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| Genes Inhibited |
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| Gene Inhibited |
F01G12.5 (let-2) |
| Description of "F01G12.5" |
let-2 encodes an alpha-2 type IV collagen, probably most closely equivalent to the human gene COL4A2 (OMIM:120090) on the basis of biological function; LET-2 is required for embryonic development and is a component of the basement membrane between muscle and hypodermis; LET-2 interacts with UNC-105, a mechanosensory ion channel of the degenerin ion channel superfamily that is expressed in muscle and required for normal growth, muscle contraction, and muscle organization. |
| KOG Annotation |
Collagens (type IV and type XIII), and related proteins
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| Evidence for Inhibition |
| ePCR |
Status: Unique_ePCR (X:16386545..16388985)
Transcript overlap: 752 nt |
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| Sliding Window |
Raw score: 626
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
| Wormbase (BLAST) |
RNAi primary |
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| External "F01G12.5" Links |
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| Simmer:F01G12.5a:Repeat_a Phenotypes |
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| Adult |
Unc
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| Simmer:F01G12.5a:Repeat_a Experiment Details |
Ace View |
| Laboratory |
NL |
| RNAi Reagent & Type |
sjj_F01G12.5a (PCR_reagent) |
| Strain |
NL4256 rrf-3(pk1426) |
| Reference |
Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." |
| Date |
2003-10-01 |
| Gene Plot of F01G12.5 |
Browse using GBrowse
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