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RNAi Experiment: Simmer:F01G12.5a:Screen Ace View of Simmer:F01G12.5a:Screen
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F01G12.5 (let-2)
Description of "F01G12.5"  let-2 encodes an alpha-2 type IV collagen, probably most closely equivalent to the human gene COL4A2 (OMIM:120090) on the basis of biological function; LET-2 is required for embryonic development and is a component of the basement membrane between muscle and hypodermis; LET-2 interacts with UNC-105, a mechanosensory ion channel of the degenerin ion channel superfamily that is expressed in muscle and required for normal growth, muscle contraction, and muscle organization.
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (X:16386545..16388985)
Transcript overlap: 752 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 626
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F01G12.5" Links  Wormbase NCBI
Simmer:F01G12.5a:Screen Phenotypes Help with Phenotypes
Larval  Lva
Adult  Unc
Simmer:F01G12.5a:Screen Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_F01G12.5a (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of F01G12.5 Browse using GBrowse
Gene Graph