Link to F10E9.6cLink to F10E9.6a.2Link to F10E9.6a.1Link to F10E9.6bRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap Link to R08F11.1RNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: Simmer:F10E9.6:Screen Ace View of Simmer:F10E9.6:Screen
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F10E9.6 (mig-10)
Description of "F10E9.6"  mig-10 encodes a protein containing a pleckstrin homology domain and a proline-rich region, and is similar to the SH2-domain containing adapter proteins Grb7 and Grb10 which are involved in receptor tyrosine kinase-mediated signal transduction; MIG-10 is likely required for signal transduction during cell migration, as it is required non-cell autonomously for excretory canal development and anterior-posterior migrations of the embryonic neurons ALM, CAN, and HSN; mig-10 mutations appear to interact genetically with mutations in all three C. elegans rac genes, ced-10, mig-2, and rac-2, suggesting partial redundancy during neuronal migration and excretory canal outgrowth; MIG-10 is expressed in many embryonic cells and in four cells in the adult head.
KOG Annotation  Growth factor receptor-bound proteins (GRB7, GRB10, GRB14)
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:8303700..8305366)
Transcript overlap: 1094 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 1031
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.92
Wormbase (BLAST) RNAi primary
External "F10E9.6" Links  Wormbase NCBI
Gene Inhibited  R08F11.1
KOG Annotation  Predicted bile acid beta-glucosidase
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 90
Relative score: 0.087 (Best raw score= for Gene )
Specificity index: 0.08
External "R08F11.1" Links  Wormbase NCBI
Simmer:F10E9.6:Screen Phenotypes Help with Phenotypes
Adult  Egl
Unc
Simmer:F10E9.6:Screen Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_F10E9.6 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of F10E9.6 Browse using GBrowse
Gene Graph
Gene Plot of R08F11.1 Browse using GBrowse
Gene Graph