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RNAi Experiment: Simmer:F10E9.7 Ace View of Simmer:F10E9.7
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F10E9.6 (mig-10)
Description of "F10E9.6"  mig-10 encodes a protein containing a pleckstrin homology domain and a proline-rich region, and is similar to the SH2-domain containing adapter proteins Grb7 and Grb10 which are involved in receptor tyrosine kinase-mediated signal transduction; MIG-10 is likely required for signal transduction during cell migration, as it is required non-cell autonomously for excretory canal development and anterior-posterior migrations of the embryonic neurons ALM, CAN, and HSN; mig-10 mutations appear to interact genetically with mutations in all three C. elegans rac genes, ced-10, mig-2, and rac-2, suggesting partial redundancy during neuronal migration and excretory canal outgrowth; MIG-10 is expressed in many embryonic cells and in four cells in the adult head.
KOG Annotation  Growth factor receptor-bound proteins (GRB7, GRB10, GRB14)
What's a KOG?
Evidence for Inhibition 
ePCR Status: Best_ePCR (III:8305089..8307513)
Transcript overlap: 594 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 552
Relative score: 0.682 (Best raw score=552 for Gene F10E9.6)
Specificity index: 0.311
Wormbase (BLAST) RNAi primary
External "F10E9.6" Links  Wormbase NCBI
Gene Inhibited  F10E9.7
Description of "F10E9.7"  Associated GO Term : zinc ion binding
Evidence for Inhibition 
ePCR Status: Top50_percentile_ePCR (III:8305089..8307513)
Transcript overlap: 495 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 453
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.456
Wormbase (BLAST) RNAi primary
External "F10E9.7" Links  Wormbase NCBI
Gene Inhibited  Y73B3A.3
Evidence for Inhibition 
Sliding Window Raw score: 231
Relative score: 0.51 (Best raw score= for Gene )
Specificity index: 0.233
External "Y73B3A.3" Links  Wormbase NCBI
Simmer:F10E9.7 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 20 - 40 %
Larval  Gro
Simmer:F10E9.7 Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_F10E9.7 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of F10E9.6 Browse using GBrowse
Gene Graph
Gene Plot of Y73B3A.3 Browse using GBrowse
Gene Graph
Gene Plot of F10E9.7 Browse using GBrowse
Gene Graph