RNAi Experiment: Simmer:F18A1.2 |
Ace View of Simmer:F18A1.2
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Genes Inhibited |
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Gene Inhibited |
F18A1.2 (lin-26) |
Description of "F18A1.2" |
lin-26 encodes a putative C2H2 zinc finger-containing protein required for proper differentiation of ectodermal and mesodermal epithelial cells; LIN-26 is expressed in many different cell types including the rectal rep cells, the somatic gonad, glial cells, and hypodermal cells; ectopic LIN-26 expression during embryogenesis induces epithelial-like cell fates suggesting that LIN-26 is sufficient for epithelial differentiation. |
Evidence for Inhibition |
ePCR |
Status: Best_ePCR (II:7682506..7683581)
Transcript overlap: 939 nt |
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Sliding Window |
Raw score: 918
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.777 |
Wormbase (BLAST) |
RNAi primary |
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External "F18A1.2" Links |
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Gene Inhibited |
F18A1.3 (lir-1) |
Description of "F18A1.3" |
LIR-1 has no obvious effect on development when ectopically expressed in embryos, despite having a primary sequence closely similar to that of LIN-26. |
Evidence for Inhibition |
ePCR |
Status: Bottom50_percentile_ePCR (II:7682506..7683581)
Transcript overlap: 326 nt |
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Sliding Window |
Raw score: 263
Relative score: 0.286 (Best raw score= for Gene )
Specificity index: 0.223 |
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External "F18A1.3" Links |
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Simmer:F18A1.2 Phenotypes |
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Embryonic |
Emb Penetrance 100 % |
Simmer:F18A1.2 Experiment Details |
Ace View |
Laboratory |
NL |
RNAi Reagent & Type |
sjj_F18A1.2 (PCR_reagent) |
Strain |
NL4256 rrf-3(pk1426) |
Reference |
Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." |
Date |
2003-10-01 |
Gene Plot of F18A1.2 |
Browse using GBrowse
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Gene Plot of F18A1.3 |
Browse using GBrowse
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