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RNAi Experiment: Simmer:F18A1.5 Ace View of Simmer:F18A1.5
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F18A1.5
Description of "F18A1.5"  F18A1.5 encodes the C. elegans ortholog of the replication protein A (RPA) large subunit; by homology, the F18A1.5 gene product is predicted to function as a DNA binding and oligonucleotide oligosaccharide binding (OB) protein that is required for DNA replication, repair, and recombination; large-scale RNAi screens indicate that the product of F18A1.5 is essential for embryonic development, and that in yeast two-hybrid assays interacts with the product of M04F3.1, the RPA medium subunit; in situ hybridization studies indicate that F18A1.5 transcripts are expressed in germ cells.
KOG Annotation  Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (II:7664898..7666054)
Transcript overlap: 972 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 867
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F18A1.5" Links  Wormbase NCBI
Simmer:F18A1.5 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 100 %
Simmer:F18A1.5 Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_F18A1.5 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of F18A1.5 Browse using GBrowse
Gene Graph