Ace View of Simmer:F22B5.1 | |||||
Gene Inhibited | F22B5.1 (evl-20) | ||||
Description of "F22B5.1" | evl-20 encodes a functional ortholog of human ADP-ribosylation factor-like protein 2 (ARL2; OMIM:601175), with evl-20(ar103) mutants being rescued by transgenic human ARL2 but not ARL1 or ARL3-7; EVL-20 is required for cortical microtubule formation during cytokinesis and morphogenesis; EVL-20 is required for vulval, gonadal, and male tail development, as well as for embryonic mitosis, hypodermal enclosure, and elongation; EVL-20 is expressed in migrating hypodermal embryonic cells, larval vulval and somatic gonad cells, larval and adult neurons, and adult male proctodeal cells, being subcellularly associated with both the cell cortex and astral microtubules. | ||||
KOG Annotation  | GTP-binding ADP-ribosylation factor-like protein ARL2 |
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Evidence for Inhibition | |||||
External "F22B5.1" Links | |||||
Gene Inhibited | F22B5.2 (eif-3.G) | ||||
Description of "F22B5.2" | eif-3. | ||||
KOG Annotation  | Translation initiation factor 3, subunit g (eIF-3g) |
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Evidence for Inhibition |
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External "F22B5.2" Links | |||||
Embryonic | Emb Penetrance 20 - 40 % | ||||
Larval | Gro |
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Adult | Pvl Rup Stp |
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Laboratory | NL | ||||
RNAi Reagent & Type | sjj_F22B5.1 (PCR_reagent) | ||||
Strain | NL4256 rrf-3(pk1426) | ||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||
Date | 2003-10-01 | ||||
Gene Plot of F22B5.1 | |||||
Gene Plot of F22B5.2 | |||||