Ace View of Simmer:F23F12.6 | |||
Gene Inhibited | F23F12.6 (rpt-3) | ||
Description of "F23F12.6" | rpt-3 encodes a triple A ATPase subunit of the 26S proteasome's 19S regulatory particle (RP) base subcomplex; RPT-3 is required for embryonic, larval, and germline development and by homology, is predicted to function in unfolding protein substrates and translocating them into the core proteolytic particle (CP) of the proteasome. | ||
KOG Annotation  | 26S proteasome regulatory complex, ATPase RPT3 |
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Evidence for Inhibition | |||
External "F23F12.6" Links | |||
Embryonic | Emb Penetrance 100 % | ||
Laboratory | NL | ||
RNAi Reagent & Type | sjj_F23F12.6 (PCR_reagent) | ||
Strain | NL4256 rrf-3(pk1426) | ||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||
Date | 2003-10-01 | ||
Gene Plot of F23F12.6 | |||