Ace View of Simmer:F26B1.7:Screen_A | |||
Gene Inhibited | F26B1.7 (let-381) | ||
Description of "F26B1.7" | let-381 encodes a forkhead transcription factor and was identified in a screen for essential genes; let-381 is essential for development at different times as mutants exhibit embryonic and early larval lethality, with a few developing to sterile adults; inactivation of let-381 using RNA interference results in adults with mesodermal cell lineage defects and a reduced number of coelomocytes; reporter-gene assays indicate LET-318 is expressed when the embryo starts to elongate and continues to be expressed through all larval stages and into the adult. | ||
KOG Annotation  | Transcription factor of the Forkhead/HNF3 family |
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Evidence for Inhibition | |||
External "F26B1.7" Links | |||
Adult | Dpy Pvl Unc |
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Laboratory | NL | ||
RNAi Reagent & Type | sjj_F26B1.7 (PCR_reagent) | ||
Strain | NL4256 rrf-3(pk1426) | ||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||
Date | 2003-10-01 | ||
Gene Plot of F26B1.7 | |||