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RNAi Experiment: Simmer:F26B1.7:Screen_B Ace View of Simmer:F26B1.7:Screen_B
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F26B1.7 (let-381)
Description of "F26B1.7"  let-381 encodes a forkhead transcription factor and was identified in a screen for essential genes; let-381 is essential for development at different times as mutants exhibit embryonic and early larval lethality, with a few developing to sterile adults; inactivation of let-381 using RNA interference results in adults with mesodermal cell lineage defects and a reduced number of coelomocytes; reporter-gene assays indicate LET-318 is expressed when the embryo starts to elongate and continues to be expressed through all larval stages and into the adult.
KOG Annotation  Transcription factor of the Forkhead/HNF3 family
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:6322398..6323567)
Transcript overlap: 571 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 488
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F26B1.7" Links  Wormbase NCBI
Simmer:F26B1.7:Screen_B Phenotypes Help with Phenotypes
Larval  Gro
Adult  Dpy
Pvl
Unc
Simmer:F26B1.7:Screen_B Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_F26B1.7 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of F26B1.7 Browse using GBrowse
Gene Graph