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RNAi Experiment: Simmer:F33A8.1 Ace View of Simmer:F33A8.1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F33A8.1 (let-858)
Description of "F33A8.1"  let-858 encodes nucampholin, a highly conserved protein rich in acidic and basic residues that also shares some similarity to eukaryotic initiation factor eIF-4 gamma; LET-858 is required for early embryogenesis and tissue differentiation and is expressed ubiquitously throughout development; LET-858 localizes to nuclei where it overlaps, but is not restricted to, chromosomal regions; based upon its sequence and localization, LET-858 is likely to be involved in protein synthesis and/or RNA binding.
KOG Annotation  Uncharacterized conserved protein
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (II:11026727..11027874)
Transcript overlap: 1043 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 1001
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F33A8.1" Links  Wormbase NCBI
Simmer:F33A8.1 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 100 %
Simmer:F33A8.1 Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_F33A8.1 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of F33A8.1 Browse using GBrowse
Gene Graph