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RNAi Experiment: Simmer:F43C1.2 Ace View of Simmer:F43C1.2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F43C1.2 (mpk-1)
Description of "F43C1.2"  mpk-1 encodes a mitogen-activated protein (MAP) kinase that acts in the vulval precursor cells to affect LET-60(Ras)-mediated induction of vulval cell fates, and also affects larval viability, morphology of the male spicules, and acts in combination with mek-2 to permit germ cell exit from the pachytene stage of first meiotic prophase; both LIN-1 and LIN-31 act genetically downstream of mpk-1 with respect to vulval induction, and LIN-1 and LIN-31 are substrates for MPK-1 in vitro.
KOG Annotation  Mitogen-activated protein kinase
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:4217371..4218826)
Transcript overlap: 815 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 773
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F43C1.2" Links  Wormbase NCBI
Simmer:F43C1.2 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 20 - 40 %
Simmer:F43C1.2 Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_F43C1.2 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of F43C1.2 Browse using GBrowse
Gene Graph