Link to F46A9.4RNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to F46A9.5.3Link to F46A9.5.2Link to F46A9.5.1geneMap
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RNAi Experiment: Simmer:F46A9.4:Screen_B Ace View of Simmer:F46A9.4:Screen_B
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F46A9.4 (skr-2)
Description of "F46A9.4"  skr-2 encodes a homolog of Skp1 in S. cerevisiae, a core component of the SCF (Skp1p, Cullin, F-box) ubiquitin-ligase complex that facilitates ubiquitin-mediated protein degradation; SKR-2 is required for the restraint of cell proliferation, progression through the pachytene stage of meiosis, and the formation of bivalent chromosomes at diakinesis; SKR-2::GFP is detected exclusively in the intestine.
KOG Annotation  SCF ubiquitin ligase, Skp1 component
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:9469370..9470527)
Transcript overlap: 622 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 496
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F46A9.4" Links  Wormbase NCBI
Simmer:F46A9.4:Screen_B Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 50 - 80 %
Simmer:F46A9.4:Screen_B Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_F46A9.4 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of F46A9.4 Browse using GBrowse
Gene Graph