RNAi Experiment: Simmer:F54C8.2 |
Ace View of Simmer:F54C8.2
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Genes Inhibited |
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Gene Inhibited |
F54C8.2 |
Description of "F54C8.2" |
Associated GO Term : DNA binding |
KOG Annotation  |
Histones H3 and H4
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (III:9433716..9434907)
Transcript overlap: 786 nt |
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Sliding Window |
Raw score: 681
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.902 |
Wormbase (BLAST) |
RNAi primary |
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External "F54C8.2" Links |
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Gene Inhibited |
F58A4.3 (hcp-3) |
Description of "F58A4.3" |
The hcp-3 gene encodes a centromere protein (CENP)-A homolog required for kinetochore function; inactivation of hcp-3 in one-cell embryos by RNAi causes a complete loss of kinetochores, with total failure of chromosomes to segregate properly during mitosis, to recruit components to the kinetochore other than HCP-3, or to assemble a stable mitotic spindle; in addition, HCP-4 fails to localize properly to the kinetochore in hcp-3(RNAi) embryos. |
KOG Annotation  |
Histones H3 and H4
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Evidence for Inhibition |
Sliding Window |
Raw score: 74
Relative score: 0.109 (Best raw score= for Gene )
Specificity index: 0.098 |
Wormbase (BLAST) |
RNAi secondary |
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External "F58A4.3" Links |
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Simmer:F54C8.2 Phenotypes |
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Embryonic |
Emb Penetrance 100 % |
Adult |
Pvl Rup
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Simmer:F54C8.2 Experiment Details |
Ace View |
Laboratory |
NL |
RNAi Reagent & Type |
sjj_F54C8.2 (PCR_reagent) |
Strain |
NL4256 rrf-3(pk1426) |
Reference |
Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." |
Date |
2003-10-01 |
Gene Plot of F58A4.3 |
Browse using GBrowse
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Gene Plot of F54C8.2 |
Browse using GBrowse
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