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RNAi Experiment: Simmer:F54C8.2 Ace View of Simmer:F54C8.2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F54C8.2
Description of "F54C8.2"  Associated GO Term : DNA binding
KOG Annotation  Histones H3 and H4
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:9433716..9434907)
Transcript overlap: 786 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 681
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.902
Wormbase (BLAST) RNAi primary
External "F54C8.2" Links  Wormbase NCBI
Gene Inhibited  F58A4.3 (hcp-3)
Description of "F58A4.3"  The hcp-3 gene encodes a centromere protein (CENP)-A homolog required for kinetochore function; inactivation of hcp-3 in one-cell embryos by RNAi causes a complete loss of kinetochores, with total failure of chromosomes to segregate properly during mitosis, to recruit components to the kinetochore other than HCP-3, or to assemble a stable mitotic spindle; in addition, HCP-4 fails to localize properly to the kinetochore in hcp-3(RNAi) embryos.
KOG Annotation  Histones H3 and H4
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 74
Relative score: 0.109 (Best raw score= for Gene )
Specificity index: 0.098
Wormbase (BLAST) RNAi secondary
External "F58A4.3" Links  Wormbase NCBI
Simmer:F54C8.2 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 100 %
Adult  Pvl
Rup
Simmer:F54C8.2 Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_F54C8.2 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of F58A4.3 Browse using GBrowse
Gene Graph
Gene Plot of F54C8.2 Browse using GBrowse
Gene Graph