RNAi Experiment: Simmer:F57B10.12:Screen_B |
Ace View of Simmer:F57B10.12:Screen_B
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Genes Inhibited |
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Gene Inhibited |
F57B10.12 (mei-2) |
Description of "F57B10.12" |
mei-2 encodes a novel protein that contains a region similar to the p80-targeting subunit of katanin that is required for embryonic viability, alignment of chromosomes at the metaphase plate, and establishment of the oocyte meiotic spindle together with MEI-1; can interact with MEI-1 in HeLa cells and this complex can function to disassemble microtubules, expressed in the germ line, throughout the cytoplasm of most mature oocytes within the proximal gonad, and localization is mutually dependent upon MEI-1 |
Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (I:6564820..6565987)
Transcript overlap: 894 nt |
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Sliding Window |
Raw score: 810
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "F57B10.12" Links |
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Simmer:F57B10.12:Screen_B Phenotypes |
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Embryonic |
Emb Penetrance 100 % |
Simmer:F57B10.12:Screen_B Experiment Details |
Ace View |
Laboratory |
NL |
RNAi Reagent & Type |
sjj_F57B10.12 (PCR_reagent) |
Strain |
NL4256 rrf-3(pk1426) |
Reference |
Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." |
Date |
2003-10-01 |
Gene Plot of F57B10.12 |
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