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RNAi Experiment: Simmer:F57B10.12:Screen_B Ace View of Simmer:F57B10.12:Screen_B
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F57B10.12 (mei-2)
Description of "F57B10.12"  mei-2 encodes a novel protein that contains a region similar to the p80-targeting subunit of katanin that is required for embryonic viability, alignment of chromosomes at the metaphase plate, and establishment of the oocyte meiotic spindle together with MEI-1; can interact with MEI-1 in HeLa cells and this complex can function to disassemble microtubules, expressed in the germ line, throughout the cytoplasm of most mature oocytes within the proximal gonad, and localization is mutually dependent upon MEI-1
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:6564820..6565987)
Transcript overlap: 894 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 810
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F57B10.12" Links  Wormbase NCBI
Simmer:F57B10.12:Screen_B Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 100 %
Simmer:F57B10.12:Screen_B Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_F57B10.12 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of F57B10.12 Browse using GBrowse
Gene Graph