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RNAi Experiment: Simmer:F58E6.10:Repeat_a Ace View of Simmer:F58E6.10:Repeat_a
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F58E6.10 (unc-42)
Description of "F58E6.10"  unc-42 encodes a paired-like homeodomain protein of the Q50 class; UNC-42 is required to specify the fate of ASH sensory neurons, AVA, AVD, and AVE interneurons, and a subset of motor neurons; unc-42 mutants fail to express cell-surface receptors required for differentiated neuronal function (sra-6, srb-6, glr-1, glr-5, and glr-6); UNC-42 is also required for AVKR and HSNL growth cones to follow the PVPR and PVQL pioneer axons, for axonal outgrowth in the backward command interneurons AVA, AVD, and AVE, and for inhibition of ectopic FMRFamide-positive and GABAergic axons; unc-42 mutants are defective in mechanosensation, backward motion, and regulation of egg-laying.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (V:9767012..9768047)
Transcript overlap: 405 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 324
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F58E6.10" Links  Wormbase NCBI
Simmer:F58E6.10:Repeat_a Phenotypes Help with Phenotypes
Adult  Unc
Simmer:F58E6.10:Repeat_a Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_F58E6.10 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of F58E6.10 Browse using GBrowse
Gene Graph