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RNAi Experiment: Simmer:H06O01.1:Screen_A Ace View of Simmer:H06O01.1:Screen_A
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  H06O01.1 (pdi-3)
Description of "H06O01.1"  pdi-3 encodes a protein disulfide isomerase (PDI) required for normal cuticle collagen deposition and, subliminally, for maintenance of normal body shape; PDI-3 has both PDI and calcium-dependent transglutaminase activity in vitro, crosslinking proteins through a gamma-glutamyl epsilon-lysine dual residue; PDI-3 is homologous to the human PDI ERp60, as well as a homolog in the dog heartworm Dirofilaria immitis that is required for larval molting; the joint PDI/transglutaminase activity of PDI-3 is biochemically conserved in nematodes and mammals; pdi-3 is constitutively and broadly expressed, particularly in gut and hypodermis.
KOG Annotation  Protein disulfide isomerase (prolyl 4-hydroxylase beta subunit)
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:7016907..7017934)
Transcript overlap: 797 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 692
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "H06O01.1" Links  Wormbase NCBI
Simmer:H06O01.1:Screen_A Phenotypes Help with Phenotypes
Adult  Sma
Simmer:H06O01.1:Screen_A Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_H06O01.1 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of H06O01.1 Browse using GBrowse
Gene Graph