| RNAi Experiment: Simmer:K04H4.1 |
Ace View of Simmer:K04H4.1
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| Genes Inhibited |
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| Gene Inhibited |
K04H4.1 (emb-9) |
| Description of "K04H4.1" |
emb-9 encodes the alpha-1 chain of Type IV basement membrane collagen most closely equivalent to human COL4A1 (OMIM:120130) on the basis of biological function; EMB-9 forms heterotrimeric Type IV collagen with LET-2, the alpha-2-like chain, and is required for the assembly and/or secretion of LET-2; EMB-9 is essential for embryonic morphogenesis, particularly epidermal elongation, and for larval development; EMB-9 is expresed primarily by body wall muscles and some somatic cells of the gonad and is detected in nearly all basement membranes. |
| Evidence for Inhibition |
| ePCR |
Status: Unique_ePCR (III:9341202..9342265)
Transcript overlap: 964 nt |
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| Sliding Window |
Raw score: 922
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
| Wormbase (BLAST) |
RNAi primary |
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| External "K04H4.1" Links |
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| Simmer:K04H4.1 Phenotypes |
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| Larval |
Lva
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| Adult |
Ste
brood size (6 out of 10)
Unc
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| Simmer:K04H4.1 Experiment Details |
Ace View |
| Laboratory |
NL |
| RNAi Reagent & Type |
sjj_K04H4.1 (PCR_reagent) |
| Strain |
NL4256 rrf-3(pk1426) |
| Reference |
Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." |
| Date |
2003-10-01 |
| Gene Plot of K04H4.1 |
Browse using GBrowse
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