RNAi Experiment: Simmer:K07A12.3:Screen_B |
Ace View of Simmer:K07A12.3:Screen_B
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Genes Inhibited |
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Gene Inhibited |
K07A12.3 (asg-1) |
Description of "K07A12.3" |
asg-1 encodes a homolog of the proton-translocating F0 ATP synthase complex subunit g; by homology, ASG-1 is predicted to function in ATP synthesis, although its precise role in ATP anabolism is not yet known; in C. elegans, asg-1 activity is required for transposon silencing in the germline, suggesting that healthy energy metabolism is necessary for this process; in addition, large-scale RNAi screens indicate that asg-1 activity is required for embryonic and germline development, normal post-embryonic growth rates, and normal body morphology. |
KOG Annotation  |
Mitochondrial F1F0-ATP synthase, subunit g/ATP20
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (I:8692669..8693549)
Transcript overlap: 477 nt |
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Sliding Window |
Raw score: 435
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "K07A12.3" Links |
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Gene Inhibited |
K07A12.5 |
Evidence for Inhibition |
ePCR |
Transcript overlap: 65 nt |
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Wormbase (BLAST) |
RNAi primary |
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External "K07A12.5" Links |
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Simmer:K07A12.3:Screen_B Phenotypes |
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Embryonic |
Emb Penetrance 20 - 40 % |
Larval |
Gro
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Adult |
Stp
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Simmer:K07A12.3:Screen_B Experiment Details |
Ace View |
Laboratory |
NL |
RNAi Reagent & Type |
sjj_K07A12.3 (PCR_reagent) |
Strain |
NL4256 rrf-3(pk1426) |
Reference |
Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." |
Date |
2003-10-01 |
Gene Plot of K07A12.3 |
Browse using GBrowse
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Gene Plot of K07A12.5 |
Browse using GBrowse
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