Ace View of Simmer:K09C4.3 | ||||||
Gene Inhibited | F26D10.3 (hsp-1) | |||||
Description of "F26D10.3" | hsp-1 encodes hsp70A, a member of the heat shock family of proteins; hsp70A is closely related to the Drosophila heat inducible hsp70s and the S. cerevisiae SSA hsp70 subfamily; the hsp-1 gene is normally expressed throughout development and upon heat-shock the hsp-1 mRNA is enhanced 2-6 fold; down-regulation of hsp-1 via RNA interference results in a small reduction in the life-span of an age-1 mutant indicating that hsp-1 may play some role in regulating longevity. | |||||
KOG Annotation  | Molecular chaperones HSP70/HSC70, HSP70 superfamily |
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Evidence for Inhibition |
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External "F26D10.3" Links | ||||||
Gene Inhibited | K09C4.3 (hsp-2) | |||||
Evidence for Inhibition |
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External "K09C4.3" Links | ||||||
Embryonic | Emb Penetrance 20 - 40 % | |||||
Larval | Lva |
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Adult | Ste
brood size (1 out of 5) Unc |
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Laboratory | NL | |||||
RNAi Reagent & Type | sjj_K09C4.3 (PCR_reagent) | |||||
Strain | NL4256 rrf-3(pk1426) | |||||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | |||||
Date | 2003-10-01 | |||||
Gene Plot of F26D10.3 | ||||||
Gene Plot of K09C4.3 | ||||||