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RNAi Experiment: Simmer:K09C4.3 Ace View of Simmer:K09C4.3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F26D10.3 (hsp-1)
Description of "F26D10.3"  hsp-1 encodes hsp70A, a member of the heat shock family of proteins; hsp70A is closely related to the Drosophila heat inducible hsp70s and the S. cerevisiae SSA hsp70 subfamily; the hsp-1 gene is normally expressed throughout development and upon heat-shock the hsp-1 mRNA is enhanced 2-6 fold; down-regulation of hsp-1 via RNA interference results in a small reduction in the life-span of an age-1 mutant indicating that hsp-1 may play some role in regulating longevity.
KOG Annotation  Molecular chaperones HSP70/HSC70, HSP70 superfamily
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 163
Relative score: 0.229 (Best raw score= for Gene )
Specificity index: 0.186
Wormbase (BLAST) RNAi secondary
External "F26D10.3" Links  Wormbase NCBI
Gene Inhibited  K09C4.3 (hsp-2)
Evidence for Inhibition 
Sliding Window Raw score: 713
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.814
Wormbase (BLAST) RNAi primary
External "K09C4.3" Links  Wormbase NCBI
Simmer:K09C4.3 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 20 - 40 %
Larval  Lva
Adult  Ste brood size (1 out of 5)
Unc
Simmer:K09C4.3 Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_K09C4.3 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of F26D10.3 Browse using GBrowse
Gene Graph
Gene Plot of K09C4.3 Browse using GBrowse
Gene Graph