Ace View of Simmer:R09B3.4:Screen_A | |||
Gene Inhibited | R09B3.4 (ubc-12) | ||
Description of "R09B3.4" | The ubc-12 gene encodes a ubiquitin-conjugating enzyme whose substrate is NED-8, and which is required for both embryogenesis and terminal hypodermal differentiation; ubc-12(RNAi) mutants either arrest during embryonic development or show pleotropic defects (e.g., vulval eversion during the L4 stage), as well as defective alae. | ||
KOG Annotation  | Ubiquitin-protein ligase |
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Evidence for Inhibition | |||
External "R09B3.4" Links | |||
Embryonic | Emb Penetrance 20 - 40 % | ||
Larval | Gro |
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Adult | Pvl Stp |
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Phenotype | Unclassified
Thin |
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Laboratory | NL | ||
RNAi Reagent & Type | sjj_R09B3.4 (PCR_reagent) | ||
Strain | NL4256 rrf-3(pk1426) | ||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||
Date | 2003-10-01 | ||
Gene Plot of R09B3.4 | |||