Link to R10E11.1aLink to R10E11.1bRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to F40F12.7.2Link to F40F12.7.1Link to K03H1.10.2Link to K03H1.10.1geneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: Simmer:R10E11.1 Ace View of Simmer:R10E11.1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  R10E11.1 (cbp-1)
Description of "R10E11.1"  cbp-1 encodes a homolog of the mammalian transcriptional cofactors CBP (OMIM:600140) and p300 (E1A-BINDING PROTEIN, 300-KD; OMIM:602700) that have been shown to possess histone acetyltransferase activity, and which, when mutated, lead to Rubinstein-Taybi syndrome (OMIM:180849) and colorectal cancer (OMIM:114500); at least one splicing form of CBP-1 exhibits histone acetyltransferase (HAT) activity in vitro and has a glutamine/asparagine-rich domain; CBP-1 is required during embryogenesis for differentiation of all non-neuronal somatic cell types; CBP-1 is expressed very early in embryogenesis, suggesting that it may interact with maternally provided transcription factors, such as SKN-1, to specific developmental fates.
KOG Annotation  CREB binding protein/P300 and related TAZ Zn-finger proteins
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:9770407..9771580)
Transcript overlap: 1174 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 1153
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "R10E11.1" Links  Wormbase NCBI
Simmer:R10E11.1 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 100 %
Simmer:R10E11.1 Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_R10E11.1 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of R10E11.1 Browse using GBrowse
Gene Graph