| Ace View of Simmer:T20B12.8 | |||||||||
| Gene Inhibited | T20B12.8 (hmg-4) | ||||||||
| Description of "T20B12.8" | hmg-4 encodes a protein with strong similarity to the highly conserved high mobility group protein SSRP1 (structure-specific DNA recognition protein); by homology, HMG-4 is predicted to be a member of the FACT (facilitates chromatin transcription) complex that functions as a transcription elongation factor; RNAi experiments indicate that hmg-4 is required for locomotion and larval development, and required redundantly with hmg-3, its paralog, for embryonic development. | ||||||||
| KOG Annotation | Nucleosome-binding factor SPN, POB3 subunit |
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| Evidence for Inhibition |
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| External "T20B12.8" Links |   |
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| Gene Inhibited | C32F10.5 (hmg-3) | ||||||||
| Description of "C32F10.5" | Associated GO Term : DNA binding | ||||||||
| KOG Annotation | Nucleosome-binding factor SPN, POB3 subunit |
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| Evidence for Inhibition |
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| External "C32F10.5" Links | |
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| Larval | Lva |
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| Adult | Unc |
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| Laboratory | NL | ||||||||
| RNAi Reagent & Type | sjj_T20B12.8 (PCR_reagent) | ||||||||
| Strain | NL4256 rrf-3(pk1426) | ||||||||
| Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||||||||
| Date | 2003-10-01 | ||||||||
| Gene Plot of T20B12.8 | |||||||||
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| Gene Plot of C32F10.5 | |||||||||
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