Link to T28C6.6RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi 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to T28C6.4RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi 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ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap Link to W05B2.4Link to W05B2.6RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi 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F52B11.4Link to W05B2.6geneMap Link to B0222.10Link to B0222.6RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi 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F11G11.10RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi 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Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: Simmer:T28C6.6:Repeat_a Ace View of Simmer:T28C6.6:Repeat_a
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T28C6.6 (col-3)
Description of "T28C6.6"  col-3 encodes a collagen protein that affects body morphogenesis, larval viability, and locomotion in large scale RNAi screens; mRNA is expressed during all developmental stages examined (in embryos, during the L2 to dauer molt, during the dauer to L4 larval molt, and during the L4 to adult molt).
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (IV:8824571..8825966)
Transcript overlap: 924 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 861
Relative score: 0.987 (Best raw score= for Gene )
Specificity index: 0.229
Wormbase (BLAST) RNAi primary
External "T28C6.6" Links  Wormbase NCBI
Gene Inhibited  T15B7.3 (col-143)
Description of "T15B7.3"  Associated GO Term : structural constituent of cuticle
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 360
Relative score: 0.413 (Best raw score= for Gene )
Specificity index: 0.096
External "T15B7.3" Links  Wormbase NCBI
Gene Inhibited  T28C6.4 (col-117)
Description of "T28C6.4"  Associated GO Term : structural constituent of cuticle
Evidence for Inhibition 
Sliding Window Raw score: 872
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.232
Wormbase (BLAST) RNAi primary
External "T28C6.4" Links  Wormbase NCBI
Gene Inhibited  B0222.8 (col-10)
Description of "B0222.8"  col-10 encodes a collagen protein; expressed exclusively in hypodermal cells
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 240
Specificity index: 0.064
External "B0222.8" Links  Wormbase NCBI
Gene Inhibited  W05B2.6 (col-92)
Description of "W05B2.6"  Associated GO Term : structural constituent of cuticle
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 124
Relative score: 0.142 (Best raw score= for Gene )
Specificity index: 0.033
Wormbase (BLAST) RNAi primary
External "W05B2.6" Links  Wormbase NCBI
Gene Inhibited  W05B2.5 (col-93)
Description of "W05B2.5"  Associated GO Term : structural constituent of cuticle
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 106
Relative score: 0.122 (Best raw score= for Gene )
Specificity index: 0.028
External "W05B2.5" Links  Wormbase NCBI
Gene Inhibited  Y2H9A.3 (col-162)
Description of "Y2H9A.3"  Associated GO Term : structural constituent of cuticle
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 68
Relative score: 0.078 (Best raw score= for Gene )
Specificity index: 0.018
External "Y2H9A.3" Links  Wormbase NCBI
Gene Inhibited  W05B2.1 (col-94)
Description of "W05B2.1"  Associated GO Term : structural constituent of cuticle
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 129
Relative score: 0.148 (Best raw score= for Gene )
Specificity index: 0.034
Wormbase (BLAST) RNAi primary
External "W05B2.1" Links  Wormbase NCBI
Gene Inhibited  B0222.6 (col-144)
Description of "B0222.6"  Associated GO Term : structural constituent of cuticle
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 240
Relative score: 0.275 (Best raw score= for Gene )
Specificity index: 0.064
External "B0222.6" Links  Wormbase NCBI
Gene Inhibited  F55C10.2 (col-154)
Description of "F55C10.2"  Associated GO Term : structural constituent of cuticle
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 62
Relative score: 0.071 (Best raw score= for Gene )
Specificity index: 0.017
Wormbase (BLAST) RNAi secondary
External "F55C10.2" Links  Wormbase NCBI
Gene Inhibited  F11G11.10 (col-17)
Description of "F11G11.10"  col-17 encodes a collagen which is expressed in all developmental stages except eggs, like col-15, col-16, and col-20; collagen genes with this expression pattern may be used for synthesis of cuticles after the L1 stage (e.g., the L4 cuticle).
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 175
Relative score: 0.201 (Best raw score= for Gene )
Specificity index: 0.047
External "F11G11.10" Links  Wormbase NCBI
Gene Inhibited  C29F4.1 (col-125)
Description of "C29F4.1"  Associated GO Term : structural constituent of cuticle
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 518
Relative score: 0.594 (Best raw score= for Gene )
Specificity index: 0.138
Wormbase (BLAST) RNAi primary
External "C29F4.1" Links  Wormbase NCBI
Simmer:T28C6.6:Repeat_a Phenotypes Help with Phenotypes
Larval  Lvl
Adult  Bmd
Dpy
Unc
Simmer:T28C6.6:Repeat_a Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_T28C6.6 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of T15B7.3 Browse using GBrowse
Gene Graph
Gene Plot of T28C6.4 Browse using GBrowse
Gene Graph
Gene Plot of B0222.8 Browse using GBrowse
Gene Graph
Gene Plot of W05B2.6 Browse using GBrowse
Gene Graph
Gene Plot of T28C6.6 Browse using GBrowse
Gene Graph
Gene Plot of W05B2.5 Browse using GBrowse
Gene Graph
Gene Plot of Y2H9A.3 Browse using GBrowse
Gene Graph
Gene Plot of W05B2.1 Browse using GBrowse
Gene Graph
Gene Plot of B0222.6 Browse using GBrowse
Gene Graph
Gene Plot of C29F4.1 Browse using GBrowse
Gene Graph
Gene Plot of F55C10.2 Browse using GBrowse
Gene Graph
Gene Plot of F11G11.10 Browse using GBrowse
Gene Graph