| RNAi Experiment: Simmer:T28F12.2a |
Ace View of Simmer:T28F12.2a
|
| Genes Inhibited |
 |
| Gene Inhibited |
T28F12.2 (unc-62) |
| Description of "T28F12.2" |
unc-62 encodes a Meis-class homeodomain protein required for posterior embryonic morphogenesis, male tail morphogenesis, commissure formation by VD and DD motor neurons, vulval morphogenesis, and normal locomotion; UNC-62 is orthologous to Drosophila HOMOTHORAX; both maternal-effect unc-62 alleles and the zygotic lethal unc-62(s472) allele phenotypically resemble mutations of the caudal ortholog pal-1; RNAi of the Pbc-class ceh-20 and ceh-40 homeodomain genes strongly enhances the hypomorphic unc-62(e644) allele to give either a strong loss-of-function or null-like phenotype, while overexpression of ceh-20 enhances the lethality of some unc-62 alleles. |
| Evidence for Inhibition |
| ePCR |
Status: Unique_ePCR (V:4500401..4502669)
Transcript overlap: 703 nt |
|
| Sliding Window |
Raw score: 619
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
| Wormbase (BLAST) |
RNAi primary |
|
| External "T28F12.2" Links |
  |
| Simmer:T28F12.2a Phenotypes |
|
|
| Embryonic |
Emb Penetrance 100 % |
| Simmer:T28F12.2a Experiment Details |
Ace View |
| Laboratory |
NL |
| RNAi Reagent & Type |
sjj_T28F12.2a (PCR_reagent) |
| Strain |
NL4256 rrf-3(pk1426) |
| Reference |
Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." |
| Date |
2003-10-01 |
| Gene Plot of T28F12.2 |
Browse using GBrowse
|
 |
![Adult](JavaScript:void
window.open("/cgi-bin/rnaidb/popUpImage.cgi?imgName=N2wormfinal.png",
"RNAiDB Help","toolbar=no, location=no, directories=no,
status=no, menubar=no, scrollbars=yes, resizable=no,
copyhistory=no, width=1000, height=550"))
