Link to T28F12.2g.3Link to T28F12.2d.2Link to T28F12.2fLink to T28F12.2a.2Link to T28F12.2d.3Link to T28F12.2g.4Link to T28F12.2a.1Link to T28F12.2eLink to T28F12.2bLink to T28F12.2g.1Link to T28F12.2g.5Link to T28F12.2g.2Link to T28F12.2cLink to T28F12.2d.1RNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
RNAi Experiment: Simmer:T28F12.2a Ace View of Simmer:T28F12.2a
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T28F12.2 (unc-62)
Description of "T28F12.2"  unc-62 encodes a Meis-class homeodomain protein required for posterior embryonic morphogenesis, male tail morphogenesis, commissure formation by VD and DD motor neurons, vulval morphogenesis, and normal locomotion; UNC-62 is orthologous to Drosophila HOMOTHORAX; both maternal-effect unc-62 alleles and the zygotic lethal unc-62(s472) allele phenotypically resemble mutations of the caudal ortholog pal-1; RNAi of the Pbc-class ceh-20 and ceh-40 homeodomain genes strongly enhances the hypomorphic unc-62(e644) allele to give either a strong loss-of-function or null-like phenotype, while overexpression of ceh-20 enhances the lethality of some unc-62 alleles.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (V:4500401..4502669)
Transcript overlap: 703 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 619
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "T28F12.2" Links  Wormbase NCBI
Simmer:T28F12.2a Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 100 %
Simmer:T28F12.2a Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_T28F12.2a (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of T28F12.2 Browse using GBrowse
Gene Graph