RNAi Experiment: Simmer:W06F12.1 |
Ace View of Simmer:W06F12.1
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Genes Inhibited |
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Gene Inhibited |
W06F12.1 (lit-1) |
Description of "W06F12.1" |
lit-1 encodes a serine threonine protein kinase homolog related to the Drosophila protein Nemo that is required for embryonic viability, plays a central role in controlling the asymmetry of cell divisions during embryogenesis, and affects EMS, MS, and C lineages; acts downstream of mom-2 with respect to polarity defects and mediates larval cell fate decisions that involve POP-1, and is expressed in most embryonic and larval cells. |
Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (III:13721624..13723296)
Transcript overlap: 1165 nt |
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Sliding Window |
Raw score: 1123
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "W06F12.1" Links |
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Simmer:W06F12.1 Phenotypes |
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Embryonic |
Emb Penetrance 100 % |
Simmer:W06F12.1 Experiment Details |
Ace View |
Laboratory |
NL |
RNAi Reagent & Type |
sjj_W06F12.1 (PCR_reagent) |
Strain |
NL4256 rrf-3(pk1426) |
Reference |
Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." |
Date |
2003-10-01 |
Gene Plot of W06F12.1 |
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