Ace View of Simmer:W09C5.2:Screen_B | |||
Gene Inhibited | W09C5.2 (unc-59) | ||
Description of "W09C5.2" | unc-59, by alternative splicing, encodes two septin isoforms required (like the septins UNC-61A/B) for normal axonal migration, distal tip cell migration, and postembryonic cytokinesis (at the cellular level) and for normal locomotion and formation of the postembryonic vulva, somatic gonad, and male tail (at the organismal level); both UNC-59 and UNC-61A/B are dispensable for embryonic cytokinesis and development, but are thought to be required for all postembryonic cytokinesis; UNC-59 and UNC-61A/B depend on each other for localization to the cytokinetic furrow. | ||
KOG Annotation  | Septin family protein (P-loop GTPase) |
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Evidence for Inhibition | |||
External "W09C5.2" Links | |||
Adult | Lon Pvl Stp Unc |
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Laboratory | NL | ||
RNAi Reagent & Type | sjj_W09C5.2 (PCR_reagent) | ||
Strain | NL4256 rrf-3(pk1426) | ||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||
Date | 2003-10-01 | ||
Gene Plot of W09C5.2 | |||