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RNAi Experiment: Simmer:Y116A8C.42 Ace View of Simmer:Y116A8C.42
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y116A8C.42 (snr-1)
Description of "Y116A8C.42"  snr-1 encodes an ortholog of human small nuclear ribonucleoprotein Sm D3, a protein that forms part of a heptameric complex required for the biogenesis and function of the snRNPs that catalyze mRNA splicing; in combination with the gene that encodes the human Sm B ortholog (snr-2) snr-1 affects embryonic viability and the nuclear association and localization of P granules in embryos based on an RNAi assay, and also affects embryonic viability, growth, and fertility based on large-scale RNAi assays; snr-1 is expressed in embryos and is expressed in larvae and adults in muscles of the alimentary system, in body-wall muscle, in seam cells and other unidentified cells in larvae and in adults.
KOG Annotation  Small nuclear ribonucleoprotein Sm D3
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (IV:17087843..17088606)
Transcript overlap: 496 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 433
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y116A8C.42" Links  Wormbase NCBI
Simmer:Y116A8C.42 Phenotypes Help with Phenotypes
Adult  Ste
Simmer:Y116A8C.42 Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_Y116A8C.42 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of Y116A8C.42 Browse using GBrowse
Gene Graph