Link to Y38A8.1Link to Y38A8.2.1Link to Y38A8.2.2RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
RNAi Experiment: Simmer:Y38A8.2 Ace View of Simmer:Y38A8.2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y38A8.2 (pbs-3)
Description of "Y38A8.2"  pbs-3 encodes a B-type subunit of the 26S proteasome's 20S protease core particle; by homology, PBS-3 is predicted to function in ATP/ubiquitin-dependent nonlysosomal protein degradation; loss of pbs-3 activity via large-scale RNAi screens indicates that, in C. elegans, PBS-3 is required for embryonic and germline development, movement, normal body coloration, and normal body morphology.
KOG Annotation  20S proteasome, regulatory subunit beta type PSMB3/PUP3
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (II:4954585..4955521)
Transcript overlap: 731 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 668
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y38A8.2" Links  Wormbase NCBI
Simmer:Y38A8.2 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 100 %
Simmer:Y38A8.2 Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_Y38A8.2 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of Y38A8.2 Browse using GBrowse
Gene Graph