Link to Y38F2AL.1RNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
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RNAi Experiment: Simmer:Y38F2A_5743.j:Screen Ace View of Simmer:Y38F2A_5743.j:Screen
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y38F2AL.1
Description of "Y38F2AL.1"  Y38F2AL.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; Y38F2AL.1 is worm-specific, with obvious homologs only in C. elegans; Y38F2AL.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (IV:2324044..2326470)
Transcript overlap: 870 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 744
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y38F2AL.1" Links  Wormbase NCBI
Simmer:Y38F2A_5743.j:Screen Phenotypes Help with Phenotypes
Adult  Dpy could not be confirmed by re-testing
Unc could not be confirmed by re-testing
Simmer:Y38F2A_5743.j:Screen Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_Y38F2A_5743.j (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of Y38F2AL.1 Browse using GBrowse
Gene Graph