Ace View of Simmer:Y39A1B.3 | |||
Gene Inhibited | Y39A1B.3 (dpy-28) | ||
Description of "Y39A1B.3" | dpy-28 encodes a non-SMC condensin subunit homolog, similar to XCAP-D2 in Xenopus, Cnd1 in S. pombe, and Ycs4p in S. cerevisiae, that is required for negative, chromosome-wide regulation of X-chromosomal genes in XX but not XO animals (dosage compensation), and for some undetermined aspect of body morphogenesis; DPY-28 is part of a multiprotein 'dosage compensation' complex with DPY-26, DPY-27 and MIX-1. | ||
KOG Annotation  | Chromosome condensation complex Condensin, subunit D2 |
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Evidence for Inhibition | |||
External "Y39A1B.3" Links | |||
Embryonic | Emb Penetrance 20 - 40 % | ||
Larval | Gro |
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Adult | Dpy |
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Laboratory | NL | ||
RNAi Reagent & Type | sjj_Y39A1B.3 (PCR_reagent) | ||
Strain | NL4256 rrf-3(pk1426) | ||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||
Date | 2003-10-01 | ||
Gene Plot of Y39A1B.3 | |||