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RNAi Experiment: Simmer:Y43F4B.6 Ace View of Simmer:Y43F4B.6
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y43F4B.6 (klp-19)
Description of "Y43F4B.6"  klp-19 encodes a plus-end-directed microtubule motor protein that is most closely related to motors of the kinesin-4 family; KLP-19 activity is essential for embryonic and larval development and is required for generating a force that aligns sister chromatid kinetochores directly opposite the spindle poles thus ensuring proper holocentric chromosome segregation; KLP-19 expression is detected in embryos and in the gonad, where it is most strongly expressed in distal mitotic nuclei and in late meiotic prophase nucleoplasm; during meiosis and mitosis, KLP-19 expression is dynamic and is detected in the nucleoplasm, the spindle body, in association with condensed chromosomes (particularly between homologous chromosomes), and in the spindle interzone.
KOG Annotation  Kinesin-like protein
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:13305692..13306839)
Transcript overlap: 1031 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 989
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y43F4B.6" Links  Wormbase NCBI
Simmer:Y43F4B.6 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 100 %
Larval  Lva
Simmer:Y43F4B.6 Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_Y43F4B.6 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of Y43F4B.6 Browse using GBrowse
Gene Graph