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RNAi Experiment: Simmer:Y48G1A_54.b:Screen_B Ace View of Simmer:Y48G1A_54.b:Screen_B
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y48G1A.5 (imb-5)
Description of "Y48G1A.5"  imb-5 encodes an importin-beta-like protein orthologous to mammalian CAS proteins (cellular apoptosis susceptibility) and Saccharomyces cerevisiae CSE1 (chromosome segregation 1); IMB-5 is predicted to function in nuclear transport of proteins required for mitotic progression or apoptosis as well as in re-export of importin-alpha, a nuclear import protein; in C. elegans, IMB-5 is essential for embryogenesis and required for normal pronuclear envelope dynamics, and may also play a role in vulval morphogenesis.
KOG Annotation  Nuclear export receptor CSE1/CAS (importin beta superfamily)
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:319957..322435)
Transcript overlap: 1776 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 1713
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y48G1A.5" Links  Wormbase NCBI
Simmer:Y48G1A_54.b:Screen_B Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 100 %
Simmer:Y48G1A_54.b:Screen_B Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_Y48G1A_54.b (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of Y48G1A.5 Browse using GBrowse
Gene Graph