Link to Y48G8AR.1RNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentgeneMap Link to Y39G10AR.18aLink to Y39G10AR.18bRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi 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Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: Simmer:Y48G8A_3671.a:Screen_B Ace View of Simmer:Y48G8A_3671.a:Screen_B
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y48G8AR.1 (grh-1)
Description of "Y48G8AR.1"  grh-1 encodes a LSF/GRH transcription factor homolog required for normal cuticular synthesis and embryonic development; both GRH-1 and its Drosophila homolog GRAINYHEAD bind to DNA sites upstream of dbl-1, mab-5, and tdc-1; all three of these target genes are homologs of genes regulated by GRAINYHEAD in Drosophila; grh-1(RNAi) animals die as embryos with soft, defective cuticles, which resembles the phenotype seen in Drosophila grainyhead mutants.
KOG Annotation  Transcription factor
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:1264245..1265757)
Transcript overlap: 366 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 305
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.504
Wormbase (BLAST) RNAi primary
External "Y48G8AR.1" Links  Wormbase NCBI
Gene Inhibited  Y39G10AR.18
Description of "Y39G10AR.18"  Associated GO Term : S-adenosylmethionine-dependent methyltransferase activity
KOG Annotation  Putative protein methyltransferase involved in meiosis and transcriptional silencing (Dot1)
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 74
Relative score: 0.243 (Best raw score= for Gene )
Specificity index: 0.122
External "Y39G10AR.18" Links  Wormbase NCBI
Gene Inhibited  Y75B8A.1 (php-3)
Description of "Y75B8A.1"  Associated GO Term : DNA binding
KOG Annotation  Transcription factor Abd-B, contains HOX domain
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 61
Relative score: 0.2 (Best raw score= for Gene )
Specificity index: 0.101
External "Y75B8A.1" Links  Wormbase NCBI
Gene Inhibited  F47H4.3 (srz-46)
Evidence for Inhibition 
Sliding Window Raw score: 165
Relative score: 0.541 (Best raw score= for Gene )
Specificity index: 0.273
External "F47H4.3" Links  Wormbase NCBI
Simmer:Y48G8A_3671.a:Screen_B Phenotypes Help with Phenotypes
Larval  Lva
Lvl
Simmer:Y48G8A_3671.a:Screen_B Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_Y48G8A_3671.a (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of Y75B8A.1 Browse using GBrowse
Gene Graph
Gene Plot of Y39G10AR.18 Browse using GBrowse
Gene Graph
Gene Plot of Y48G8AR.1 Browse using GBrowse
Gene Graph
Gene Plot of F47H4.3 Browse using GBrowse
Gene Graph