Ace View of Simmer:Y49E10.1 | |||
Gene Inhibited | Y49E10.1 (rpt-6) | ||
Description of "Y49E10.1" | rpt-6 encodes a triple A ATPase that is a subunit of the 26S proteasome 19S regulatory particle (RP) base subcomplex; RPT-6 is required for embryonic and larval development and by homology, is predicted to function in unfolding protein substrates and translocating them into the core proteolytic particle (CP) of the proteasome. | ||
KOG Annotation  | 26S proteasome regulatory complex, ATPase RPT6 |
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Evidence for Inhibition | |||
External "Y49E10.1" Links | |||
Embryonic | Emb Penetrance 100 % | ||
Larval | Lva |
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Adult | Unc |
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Laboratory | NL | ||
RNAi Reagent & Type | sjj_Y49E10.1 (PCR_reagent) | ||
Strain | NL4256 rrf-3(pk1426) | ||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||
Date | 2003-10-01 | ||
Gene Plot of Y49E10.1 | |||