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RNAi Experiment: Simmer:Y54E5B.3:Screen_B Ace View of Simmer:Y54E5B.3:Screen_B
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y54E5B.3 (let-49)
Description of "Y54E5B.3"  let-49 encodes a putative mediator complex subunit zygotically required for postembryonic development and viability past larval stages, while being maternally required for germline and embryonic development; LET-49 is an ortholog of human CRSP9 (OMIM:605045) and of S. cerevisiae Med7p; Med7p is a component of a mediator complex that serves as a transcriptional coactivator, while CRSP9 mediates transcriptional activation by Sp1.
KOG Annotation  Transcriptional coactivator
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:14820407..14821476)
Transcript overlap: 713 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 609
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y54E5B.3" Links  Wormbase NCBI
Simmer:Y54E5B.3:Screen_B Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 50 - 80 %
Larval  Gro
Adult  Dpy
Pvl
Stp
Unc
Simmer:Y54E5B.3:Screen_B Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_Y54E5B.3 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of Y54E5B.3 Browse using GBrowse
Gene Graph