RNAi Experiment: Simmer:ZC308.1:Screen_A |
Ace View of Simmer:ZC308.1:Screen_A
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Genes Inhibited |
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Gene Inhibited |
ZC308.1 (gld-2) |
Description of "ZC308.1" |
gld-2 encodes the catalytic subunit of a cytoplasmic poly(A) polymerase (PAP) associated with P granules in early embryos, which encodes the central catalytic domain but lacks the normal RNA-binding (RRM) domain of eukaryotic PAPs; GLD-2 regulates the switch from mitosis to meiosis in the germline, is necessary for formation of functional sperm or oocytes, requires activation by GLD-3 for PAP activity in vitro, and contains a glutamine/asparagine-rich domain perhaps involved in epigenetic gene control. |
Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (I:6383527..6384720)
Transcript overlap: 949 nt |
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Sliding Window |
Raw score: 865
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "ZC308.1" Links |
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Simmer:ZC308.1:Screen_A Phenotypes |
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Embryonic |
Emb Penetrance 100 % |
Adult |
Ste
brood size (1 out of 5)
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Simmer:ZC308.1:Screen_A Experiment Details |
Ace View |
Laboratory |
NL |
RNAi Reagent & Type |
sjj_ZC308.1 (PCR_reagent) |
Strain |
NL4256 rrf-3(pk1426) |
Reference |
Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." |
Date |
2003-10-01 |
Gene Plot of ZC308.1 |
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