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RNAi Experiment: Simmer:ZC308.1:Screen_B Ace View of Simmer:ZC308.1:Screen_B
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  ZC308.1 (gld-2)
Description of "ZC308.1"  gld-2 encodes the catalytic subunit of a cytoplasmic poly(A) polymerase (PAP) associated with P granules in early embryos, which encodes the central catalytic domain but lacks the normal RNA-binding (RRM) domain of eukaryotic PAPs; GLD-2 regulates the switch from mitosis to meiosis in the germline, is necessary for formation of functional sperm or oocytes, requires activation by GLD-3 for PAP activity in vitro, and contains a glutamine/asparagine-rich domain perhaps involved in epigenetic gene control.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:6383527..6384720)
Transcript overlap: 949 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 865
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "ZC308.1" Links  Wormbase NCBI
Simmer:ZC308.1:Screen_B Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 50 - 80 %
Simmer:ZC308.1:Screen_B Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_ZC308.1 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of ZC308.1 Browse using GBrowse
Gene Graph