Ace View of Simmer:ZK973.g:Repeat_b | |||
Gene Inhibited | ZK973.6 (anc-1) | ||
Description of "ZK973.6" | anc-1 encodes a 8546-residue protein, orthologous of Drosophila Msp-300 and mammalian Syne proteins, which may extend more than 0.5 micrometers in vivo; ANC-1 has coiled regions, a nuclear envelope localization domain (the KASH domain) and an actin-binding domain; ANC-1 affects the positioning of nuclei and mitochondria within the cytoskeleton; ANC-1 is expressed in the cytoplasm, but localized to the nuclear periphery in an UNC-84-dependent manner. | ||
KOG Annotation  | Dystonin, GAS (Growth-arrest-specific protein), and related proteins |
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Evidence for Inhibition | |||
External "ZK973.6" Links | |||
Phenotype | WT |
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Laboratory | NL | ||
RNAi Reagent & Type | sjj_ZK973.g (PCR_reagent) | ||
Strain | NL4256 rrf-3(pk1426) | ||
Reference | Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." | ||
Date | 2003-10-01 | ||
Gene Plot of ZK973.6 | |||