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RNAi Experiment: TH:300e8 Ace View of TH:300e8
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F35G12.10 (asb-1)
Description of "F35G12.10"  asb-1 encodes a homolog of ATP synthase B, closely similar to its paralog ASB-2, that is required for embryonic viability and for the normal proliferation of germline cells; asb-1 is preferentially expressed in germline cells, while RNAi of asb-1 causes embryonic lethality and sterility with a defective progression to meiosis.
KOG Annotation  Mitochondrial F1F0-ATP synthase, subunit b/ATP4
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:4594544..4595631)
Transcript overlap: 882 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 798
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F35G12.10" Links  Wormbase NCBI
TH:300e8 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
TH:300e8 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  TH:300e8 (PCR_reagent)
Remark  Phenotype comment -- Confirmed with independent dsRNA (F35G12.10-RNA2; similar DIC phenotype, but progeny test was not embryonic lethal).
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Date  2000-11-16
Gene Plot of F35G12.10 Browse using GBrowse
Gene Graph