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RNAi Experiment: TH:302E9 Ace View of TH:302E9
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C06G4.2 (clp-1)
Description of "C06G4.2"  clp-1 encodes a calpain homolog that has significant identity to mammalian calpains over its whole length and that contains motifs typical of calpains, including a thiol (cysteine) protease active site and a Ca[2+]-binding domain; CLP-1 is required, in parallel with TRA-3 but in series with ASP-3 and ASP-3, for degenerative (necrotic-like) cell death in neurons induced by mutations such as mec-4(d), deg-3(d), or gsa-1(gf).
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:7983052..7985070)
Transcript overlap: 1381 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 1234
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C06G4.2" Links  Wormbase NCBI
TH:302E9 Phenotypes Help with Phenotypes
Phenotype  WTDIC phenotype -- Embryonic development normal
TH:302E9 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  TH:302E9 (PCR_reagent)
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Delivery Method  Injection
Date  2000-11-16
Gene Plot of C06G4.2 Browse using GBrowse
Gene Graph