Link to F11H8.1RNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentgeneMap Link to C06E8.1Link to F11H8.2RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to F11H8.2Link to C06E8.1geneMap Link to F11H8.2Link to F11H8.3RNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to F26F12.1Link to ZK1193.1geneMap
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RNAi Experiment: TH:302H4 Ace View of TH:302H4
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F11H8.1 (rfl-1)
Description of "F11H8.1"  rfl-1 (also known as cyk-5) encodes an ortholog of UBA3, a Nedd8 activating enzyme for ubiquitin-like proteins, which is required for proper cytokinesis and spindle orientation; NED-8 is presumably activated by an ULA-1/RFL-1 heterodimer.
KOG Annotation  NEDD8-activating complex, catalytic component UBA3
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:7021362..7023272)
Transcript overlap: 1102 nt
Explain types of evidence for RNAi inhibition
External "F11H8.1" Links  Wormbase NCBI
Gene Inhibited  F11H8.2
Description of "F11H8.2"  Associated GO Term : GABA-A receptor activity
KOG Annotation  GABA receptor
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 234
Relative score: 0.276 (Best raw score= for Gene )
Specificity index: 0.216
Wormbase (BLAST) RNAi primary
External "F11H8.2" Links  Wormbase NCBI
Gene Inhibited  F11H8.3 (col-8)
Description of "F11H8.3"  col-8 encodes a collagen, individually dispensable for viability and gross morphology, which is specifically expressed in dauers and adults but not in eggs or L4 larvae, like col-7, col-18, and col-19; the amino- and carboxyl-terminal cysteine-rich regions of COL-8 are most closely related to those of COL-19, COL-35, and COL-39.
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 847
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.784
Wormbase (BLAST) RNAi primary
External "F11H8.3" Links  Wormbase NCBI
TH:302H4 Phenotypes Help with Phenotypes
Phenotype  WTDIC phenotype -- Embryonic development normal
TH:302H4 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  TH:302H4 (PCR_reagent)
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Delivery Method  Injection
Date  2000-11-16
Gene Plot of F11H8.2 Browse using GBrowse
Gene Graph
Gene Plot of F11H8.3 Browse using GBrowse
Gene Graph
Gene Plot of F11H8.1 Browse using GBrowse
Gene Graph