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RNAi Experiment: TH:303h3 Ace View of TH:303h3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F43C1.2 (mpk-1)
Description of "F43C1.2"  mpk-1 encodes a mitogen-activated protein (MAP) kinase that acts in the vulval precursor cells to affect LET-60(Ras)-mediated induction of vulval cell fates, and also affects larval viability, morphology of the male spicules, and acts in combination with mek-2 to permit germ cell exit from the pachytene stage of first meiotic prophase; both LIN-1 and LIN-31 act genetically downstream of mpk-1 with respect to vulval induction, and LIN-1 and LIN-31 are substrates for MPK-1 in vitro.
KOG Annotation  Mitogen-activated protein kinase
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:4217293..4219285)
Transcript overlap: 1076 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 992
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F43C1.2" Links  Wormbase NCBI
TH:303h3 Phenotypes Help with Phenotypes
Adult  Ste
TH:303h3 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  TH:303h3 (PCR_reagent)
Remark  Phenotype comment -- Very few or no embryos found.
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Date  2000-11-16
Gene Plot of F43C1.2 Browse using GBrowse
Gene Graph