RNAi Experiment: TH:305A9 |
Ace View of TH:305A9
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Genes Inhibited |
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Gene Inhibited |
F44B9.4 (cit-1.1) |
Description of "F44B9.4" |
cit-1.1 encodes one of two C. elegans cyclin T orthologs; RNAi experiments indicate that CIT-1.1 functions redundantly with CIT-1.2 to broadly regulate embryonic transcription; by homology, CIT-1.1 and CIT-1.2 are predicted to interact with the CDK-9 kinase to form the P-TEFb transcription elongation factor that in C. elegans is required for Ser2, but not Ser5, phosphorylation in the C-terminal domain (CTD) repeat of AMA-1/Pol |
Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (III:8007729..8009952)
Transcript overlap: 1003 nt |
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Sliding Window |
Raw score: 709
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "F44B9.4" Links |
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TH:305A9 Phenotypes |
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Phenotype |
WTDIC phenotype -- Embryonic development normal
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TH:305A9 Experiment Details |
Ace View |
Laboratory |
TH |
RNAi Reagent & Type |
TH:305A9 (PCR_reagent) |
Reference |
Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." |
Delivery Method |
Injection |
Date |
2000-11-16 |
Gene Plot of F44B9.4 |
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