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RNAi Experiment: TH:305C3 Ace View of TH:305C3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T20H4.5
Description of "T20H4.5"  The T20H4.5 gene encodes an ortholog of the human gene NADH DEHYDROGENASE-UBIQUINONE FE-S PROTEIN 8 23 KDA SUBUNIT; MITOCHONDRIAL COMPLEX I TYKY SUBUNIT (NDUFS8; OMIM:602141), which when mutated leads to Leigh syndrome (OMIM:256000); the T20H4.5 protein is predicted to be mitochondrial with 52% accuracy.
KOG Annotation  NADH:ubiquinone oxidoreductase, NDUFS8/23 kDa subunit
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:7233095..7234962)
Transcript overlap: 691 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 607
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "T20H4.5" Links  Wormbase NCBI
TH:305C3 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
TH:305C3 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  TH:305C3 (PCR_reagent)
Remark  Phenotype comment -- A second independent RNA (RNA2) yielded a weaker phenotype (early larval arrest).
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Date  2000-11-16
Gene Plot of T20H4.5 Browse using GBrowse
Gene Graph