Link to F37C12.12RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: TH:305F2 Ace View of TH:305F2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F37C12.12 (mec-14)
Description of "F37C12.12"  mec-14 encodes a protein with similarity to the beta-subunits of Shaker-type potassium channels, which are members of the aldo-keto reductase superfamily; MEC-14 is required for response to gentle touch by the six touch receptor neurons, and likely functions to regulate activity of the MEC-4 and MEC-10 degenerin channels; mec-14 expression is detected solely in the touch receptor neurons and is dependent on the MEC-3 LIM domain transcription factor; proper MEC-14 localization in the touch receptor neurons is dependent on MEC-12/alpha-tubulin.
KOG Annotation  Predicted oxidoreductase
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:7190440..7192670)
Transcript overlap: 1077 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 869
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F37C12.12" Links  Wormbase NCBI
TH:305F2 Phenotypes Help with Phenotypes
Phenotype  WTDIC phenotype -- Embryonic development normal
TH:305F2 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  TH:305F2 (PCR_reagent)
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Delivery Method  Injection
Date  2000-11-16
Gene Plot of F37C12.12 Browse using GBrowse
Gene Graph