RNAi Experiment: TH:306B9 |
Ace View of TH:306B9
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Genes Inhibited |
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Gene Inhibited |
C05D11.5 |
KOG Annotation  |
Hydroxypyruvate isomerase
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Evidence for Inhibition |
ePCR |
Status: Best_ePCR (III:6410013..6411919)
Transcript overlap: 817 nt |
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Sliding Window |
Raw score: 712
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.662 |
Wormbase (BLAST) |
RNAi primary |
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External "C05D11.5" Links |
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Gene Inhibited |
C05D11.6 (nas-4) |
Description of "C05D11.6" |
nas-4 encodes a predicted extracellular matrix metalloprotease of the M12A (astacin) family that contains an N-terminal signal sequence and a catalytic domain, but no recognizable regulatory domains in the C-terminus; as loss of nas-4 activity via RNAi results in no obvious abnormalities, the precise role of NAS-4 in C. elegans development and/or behavior is not yet known; however, an NAS-4 translational reporter is expressed in the pharynx and intestine in larvae and adults, suggesting a role for NAS-4 in digestion; NAS-4 is specifically detected within cells of the pharyngeal procorpus, metacorpus, isthmus, and terminal bulb, with extracellular expression detected in the lumen of the terminal bulb and in the gut. |
KOG Annotation  |
Meprin A metalloprotease
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Evidence for Inhibition |
ePCR |
Status: Bottom50_percentile_ePCR (III:6410013..6411919)
Transcript overlap: 384 nt |
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Sliding Window |
Raw score: 363
Relative score: 0.51 (Best raw score= for Gene )
Specificity index: 0.338 |
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External "C05D11.6" Links |
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TH:306B9 Phenotypes |
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Phenotype |
WTDIC phenotype -- Embryonic development normal
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TH:306B9 Experiment Details |
Ace View |
Laboratory |
TH |
RNAi Reagent & Type |
TH:306B9 (PCR_reagent) |
Reference |
Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." |
Delivery Method |
Injection |
Date |
2000-11-16 |
Gene Plot of C05D11.6 |
Browse using GBrowse
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Gene Plot of C05D11.5 |
Browse using GBrowse
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