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RNAi Experiment: TH:308B1 Ace View of TH:308B1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F59B2.6 (zif-1)
Description of "F59B2.6"  zif-1 encodes a SOCS-box protein that promotes establishment of the germ line by targetting germline proteins for cullin-dependent degradation in non-germline (somatic) cells; ZIF-1 binds germline CCCH-(zinc)-finger proteins and the E3 ubiquitin ligase subunit elongin C (ELC-1); while ZIF-1 has no obvious homologs, it may be analogous to the Drosophila SOCS-box protein GUSTAVUS, which is required for VASA localization to the germline and which does have mammalian homologs.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:9002785..9004412)
Transcript overlap: 1363 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 1237
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F59B2.6" Links  Wormbase NCBI
TH:308B1 Phenotypes Help with Phenotypes
Phenotype  WTDIC phenotype -- Embryonic development normal
TH:308B1 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  TH:308B1 (PCR_reagent)
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Delivery Method  Injection
Date  2000-11-16
Gene Plot of F59B2.6 Browse using GBrowse
Gene Graph