RNAi Experiment: TH:314C6 |
Ace View of TH:314C6
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Genes Inhibited |
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Gene Inhibited |
F37C12.12 (mec-14) |
Description of "F37C12.12" |
mec-14 encodes a protein with similarity to the beta-subunits of Shaker-type potassium channels, which are members of the aldo-keto reductase superfamily; MEC-14 is required for response to gentle touch by the six touch receptor neurons, and likely functions to regulate activity of the MEC-4 and MEC-10 degenerin channels; mec-14 expression is detected solely in the touch receptor neurons and is dependent on the MEC-3 LIM domain transcription factor; proper MEC-14 localization in the touch receptor neurons is dependent on MEC-12/alpha-tubulin. |
KOG Annotation  |
Predicted oxidoreductase
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (III:7190308..7191999)
Transcript overlap: 994 nt |
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Sliding Window |
Raw score: 847
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "F37C12.12" Links |
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TH:314C6 Phenotypes |
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Phenotype |
WTDIC phenotype -- Embryonic development normal
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TH:314C6 Experiment Details |
Ace View |
Laboratory |
TH |
RNAi Reagent & Type |
TH:314C6 (PCR_reagent) |
Reference |
Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." |
Delivery Method |
Injection |
Date |
2000-11-16 |
Gene Plot of F37C12.12 |
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